How does a group of faculty infuse entrepreneurship into a large agricultural college? In this presentation, we describe our on-going journey with entrepreneurship in Penn State's Ag space. Since its inception in 2006, the College of Agricultural Science's Entrepreneurship Initiative has experienced several states of transition and has gained significant momentum. Our charge is to develop entrepreneurs across the college's students, faculty, alumni and external constituents. We will discuss our successes, failures and lessons learned during our journey over the last five years. Example themes discussed are enlisting the college's entrepreneurial hybrids across students, faculty and alumni, pollinating cross-university entrepreneurship networks, avoiding the blight of debating entrepreneurship and pressing on with the chore of cultivating entrepreneurship. These topics will be framed with the question: how do we keep entrepreneurship growing in Penn State's Ag space?